pWZL Neo Myr Flag MAP3K7

Properties and application
This plasmid is part of the Myristoylated Kinase Library Kit.
Depositor
William Hahn
MGLCC accession number
20520

RM350.00

Purified plasmid

Product Information

Vector backbonepWZL-Neo-Myr-Flag-DEST
Vector typeMammalian Expression, Retroviral
Bacterial resistanceAmpicillin
Growth temperature37°C
Host rangeStbl3
Cloning methodGateway Cloning
5' sequencing primerpWZL-Fwd (GAA CCT CCT CGT TCG ACC)
3' sequencing primerpWZL-Rev (TTC CGG GCC CTC ACA TTG)
Cloned geneMAP3K7
Cloned gene (alt name)mitogen-activated protein kinase kinase kinase 7, transcript variant A
GenBank IDNM_003188
SpeciesH. sapiens (human)
MutationQ356H
Entrez geneMAP3K7 (a.k.a. CSCF, FMD2, MEKK7, TAK1, TGF1a)
Tag / fusion proteinMyr (N terminal on backbone) Flag (N terminal on backbone)
CommentORFs were cloned into Gateway compatible pEntry vectors. An LR recombination reaction was performed to move the ORF to pWZL-Neo-Myr-Flag DEST such that the ORF would have 5' myristoylation and flag tags. This plasmid is part of a kinase library, and the gene has been verified, but has not been fully sequenced for minor mutations. Addgene has identified a Q356H mutation in the MAP3K7 insert. Please see the following link for plasmids from this article that are not part of the kinase library http://www.addgene.org/pubmed/17574021